Synthetic phase sensitive inversion recovery late gadolinium enhancement from post-contrast T1-mapping shows excellent agreement with conventional PSIR-LGE for diagnosing myocardial scar

  • Goran Abdula,
  • Peder Sörensson,
  • Magnus Lundin,
  • Jannike Svedin,
  • Margareta Klein,
  • Peter Kellman,
  • Andreas Sigfridsson and
  • Martin Ugander
Journal of Cardiovascular Magnetic Resonance201416 (Suppl 1) :P213

  • Published: 16 January 2014


  • Cardiac Magnetic Resonance
  • Late Gadolinium Enhancement
  • Myocardial Scar
  • Late Gadolinium Enhancement Image
  • Phase Sensitive Inversion Recovery


Cardiac magnetic resonance (CMR) imaging using phase sensitive inversion recovery (PSIR) late gadolinium enhancement (LGE) is the in vivo reference standard for assessing focal myocardial scar. Post-contrast T1-mapping by Modified Look-Locker Inversion recovery (MOLLI) can be used to generate a Synthetic PSIR LGE (SynLGE) image with an image contrast similar to conventional LGE images. We aimed to identify focal myocardial scar by SynLGE and compare its diagnostic accuracy with the reference standard LGE. We hypothesized that SynLGE has an accuracy which approaches LGE for diagnosing focal myocardial scar.


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